Skin patch hope for Parkinson's
A new skin patch may offer relief to patients in the
early stages of Parkinson's disease.
The Neupro patch, made by Schwarz Pharma, has been
licensed for use in the UK.
It delivers a drug that mimics the effects of a
naturally occurring brain chemical, which is in short
supply in people with Parkinson's.
The Parkinson's Disease Society said the patch may help
some manage their symptoms more easily.
Between 8,000 and 10,000 new cases of Parkinson's are
diagnosed in the UK every year, with 95% of cases in
those aged over 40.
At any one time, 120,000 people in the UK have the
condition.
People with the disease have a shortage of the brain
chemical dopamine, which controls connections between
nerve cells, leading to symptoms such as tremors.
'Useful addition'
Until now, patients have mostly taken a dopamine agonist
- an agent that acts directly on the dopamine receptors
in the brain - in tablet form, or through injections of
through a pump.
The patch contains a new dopamine agonist, called
rotigotine, and delivers a continuous dose of the drug
over 24 hours, so patients only having to change the
patch once a day.
Doctors say it could help people who have problems
swallowing pills and those with digestion problems that
stop oral drugs being fully absorbed.
Robert Meadowcroft, director of policy, campaigns and
information at the Parkinson's Disease Society, said:
"We are pleased that a new dopamine agonist has been
launched as a skin patch for the treatment of early
Parkinson's disease.
"Clinical trials to date have shown the patch to be safe
and effective in early stage Parkinson's patients, and a
potential option for long-term benefit."
He added: "The rotigotine patch is a useful addition to
the range of Parkinson's drugs, giving clinicians and
patients another treatment option to consider."
Dr Ray Chaudhuri, a consultant neurologist at University
Hospital Lewisham, in south London, said: "For
clinicians and people with Parkinson's, this is a new
and simple way of delivering a dopamine agonist.
"It has the potential to overcome many of the problems
associated with oral administration and may well prove
to be one of the most effective methods of delivering a
steady and continuous dose."